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Doctors, nurses and staff at the hospital in the heart of the Lake of the Ozarks region are now dealing with an onslaught of COVID-19 patients — some of them struggling to stay alive.

St. Louis County's top elected official insisted Wednesday that a mask mandate remained in place even though the county commission voted to overturn it.

States and businesses, including those in Missouri, scrambled Wednesday to change course after the federal government issued new guidance calling for the return of mask wearing in virus hot spots amid a dramatic spike in COVID-19 cases and hospitalizations nationwide.

The attorney general in Missouri has sued in an effort to halt a mask mandate that took effect Monday in the St. Louis area amid a rise in COVID-19 cases that are burdening a growing number of hospitals around the state.

The St. Louis area has become one of the first in the country to reinstate mask requirements amid a rise in cases that health officials are blaming on low vaccination rates and the highly contagious delta variant.

As the delta variant of COVID-19 makes its way through the Kansas City area, the region's medical leaders appear to be on the verge of calling for new mask mandates.

Missouri’s Republican Gov. Mike Parson on Wednesday rolled out a vaccine incentive program that includes $10,000 prizes for 900 lottery winners.

The St. Louis area is facing a third wave of COVID-19 that could cause more deaths and serious cases if residents don't get vaccinated and return to wearing masks in public, the head of the region's pandemic task force said Tuesday.

Indiana University can require its roughly 90,000 students and 40,000 employees to get vaccinated for COVID-19 under a federal judge's ruling that might be the first of its kind regarding college immunization mandates.

With the delta variant causing a surge of new COVID-19 cases and hospitalizations in southwestern Missouri, health officials have taken to going door-to-door in an effort to encourage vaccinations.

Missouri Gov. Mike Parson said the state will “probably” provide funding for a site to help handle the overflow of COVID-19 patients in Springfield, where hospitals are struggling to keep up with a surge driven by the delta variant and vaccination hesitation.